Royal Air Force Typhoon fighter aircraft have operated alongside French aircraft in a joint strike targeting an hidden munitions depot in Syrian territory used by the IS group, according to the UK's MoD.
The site, pinpointed through reconnaissance, was believed to be containing munitions and bombs, the announcement noted, and was positioned in hills just above Palmyra in central Syria.
"The RAF jets used laser-guided Paveway IV weapons to strike a several entry passages leading to the facility... early reports are that the objective was successfully hit," officials stated.
There was no sign of any civilian casualties in the operation late on Saturday and every plane involved returned safely, the defence officials confirmed.
The British jets were assisted by a Voyager refuelling tanker.
The Islamic State group - also known as Daesh - enforced jihadist rule over parts of both Syria and Iraq prior to its 2019 collapse.
"This operation shows British leadership, and commitment to operate in unison with allied nations, to stamp out any revival of Daesh and their dangerous and violent ideologies in the area," Britain's Defence Chief the minister stated.
UK warplanes have conducted overwatch operations over Syrian airspace to "prevent any attempted comeback" of IS subsequent to its defeat at the Baghuz confrontation in the year 2019, the MoD reported.
"I must thank every member of the UK armed forces who took part in this operation for their expertise and their bravery," Healey said. "They were part of a great many British personnel on duty over the festive period. This mission, to take out militants who endanger our way of life, demonstrates how UK forces are ready to step up, throughout the year, protecting the UK at home and influential overseas."
Last December, the American forces conducted what it termed a "major assault" targeting Daesh sites in the country, after an attack resulted in the deaths of two US troops and a local interpreter in Palmyra.
The U.N. reports IS still boasts roughly 5-7 thousand combatants in Syria and Iraq.